This thread recommends Winchester WLP for the 500 (supposedly per John Linebaugh himself), because it lowers pressure.
“Brian Pearce shows a 13,500 psi increase from when switching from WLPs to 350s with a 100 fps velocity increase in ruger 45 colt loads using identical charges of enforcer powder.
“. (That’s in a Handloader article)
The CCI350 has always been the other stand-out favorite.